Biological effects of hyaluronan in connective tissues, eye, skin, venous wall. Role in aging.


Hyaluronan, as most macromolecules of the extracellular matrix, are produced by the differentiated mesenchymal cells. These cells produce also enzymes degrading hyaluronan. This results in the presence of several hyaluronan pools of different molecular weights, all capable of interacting with surrounding cells, mediated by hyaluronan binding proteins and… (More)
DOI: 10.1016/j.patbio.2009.09.010


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