Biological clock dysfunction exacerbates contact hypersensitivity in mice.

@article{Takita2013BiologicalCD,
  title={Biological clock dysfunction exacerbates contact hypersensitivity in mice.},
  author={E Takita and Satoshi Yokota and Yu Tahara and Atsushi Hirao and Naoko Tabei Aoki and Yasuhiro Nakamura and Atsuhito Nakao and S Shibata},
  journal={The British journal of dermatology},
  year={2013},
  volume={168 1},
  pages={39-46}
}
BACKGROUND Immediate-type skin allergic reactions, such as passive cutaneous anaphylactic reaction, are associated with circadian rhythm, but the role of circadian mechanisms on delayed-type skin allergic reactions, such as contact hypersensitivity (CHS), remains uncertain. In mice, CHS, a T-cell-mediated immune response, is a classic model of human… CONTINUE READING