Biological chemistry and clinical potential of S-nitrosothiols.

  title={Biological chemistry and clinical potential of S-nitrosothiols.},
  author={Neil Hogg},
  journal={Free radical biology & medicine},
  volume={28 10},
  • Neil Hogg
  • Published 2000 in Free radical biology & medicine
S-Nitrosothiols are endogenous metabolites of nitric oxide that have been detected in extra- and intracellular spaces. Many biological functions of S-nitrosothiols have been described that can be categorized as being due to one or more of the following: (i) nitric oxide release, (ii) transnitrosation, (iii) S-thiolation, and (iv) direct action. This emphasizes the fact that S-nitrosothiols are more than simply nitric oxide donors. Many of the biological functions that have been described for S… CONTINUE READING

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