Biological characterization of human monoclonal antibodies to rabies virus.

@article{Dietzschold1990BiologicalCO,
  title={Biological characterization of human monoclonal antibodies to rabies virus.},
  author={Bernhard Dietzschold and Michael G. Gore and Paolo G. Casali and Yasuyoshi Ueki and Charles E. Rupprecht and Abner Louis Notkins and Hilary Prof Koprowski},
  journal={Journal of virology},
  year={1990},
  volume={64 6},
  pages={
          3087-90
        }
}
Rabies virus antigen-specific human monoclonal antibodies (MAbs) that recognized either viral glycoprotein, ribonucleoprotein, or matrix proteins were generated. Only glycoprotein-specific MAb neutralized a variety of rabies viruses and protected laboratory rodents against lethal rabies virus infection. The determinant recognized by this MAb does not appear to reside in previously defined antigenic sites of the viral glycoprotein. 

Similar Papers

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 29 CITATIONS

Study of rabies virus by Differential Scanning Calorimetry

  • Biochemistry and biophysics reports
  • 2015
VIEW 5 EXCERPTS
CITES METHODS
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 17 REFERENCES

Analysis of protective immune mechanisms induced by rabies nucleoprotein, p. 295-305

B. Dietzschold, M. Gore, +4 authors H. Koprowski
  • 1989
VIEW 1 EXCERPT

Characterization of a new virus-neutralizing epitope that denotes a sequential determinant on the rabies virus glycoprotein

H. Bunschoten, M. Gore, +4 authors A.D.M.E. Osterhaus
  • J. Gen. Virol
  • 1989
VIEW 2 EXCERPTS

Rabies in the Americas and remarks on global aspects.

  • Reviews of infectious diseases
  • 1988
VIEW 1 EXCERPT

Enzyme immunoassays: practical aspects of their methodology

J. H. Carter
  • J. Clin. Immunol
  • 1984
VIEW 1 EXCERPT

Structural basis of antibody function

D. R. Davis, H. Metzger
  • Annu. Rev. Immunol
  • 1983
VIEW 1 EXCERPT