Biological characteristics of Taxol‑resistant ovarian cancer cells and reversal of Taxol resistance by adenovirus expressing p53.

Abstract

The development of acquired drug resistance is the primary cause of chemotherapy failure in the treatment of ovarian cancer. To examine the mechanism underlying Taxol (TAX) resistance in ovarian cancer and attempt to reverse it, the present study induced a TAX‑resistant ovarian cancer cell line SKOV3/TAX using a gradient concentration increment method. The… (More)
DOI: 10.3892/mmr.2014.2784

Topics

7 Figures and Tables

Cite this paper

@article{Liu2015BiologicalCO, title={Biological characteristics of Taxol‑resistant ovarian cancer cells and reversal of Taxol resistance by adenovirus expressing p53.}, author={Qun Liu and Rui Sui and RuiRui Li and Jinwei Miao and Jian Liu}, journal={Molecular medicine reports}, year={2015}, volume={11 2}, pages={1292-7} }