Biological characterisation of a recombinant Atlantic salmon type I interferon synthesized in Escherichia coli.

@article{Ooi2008BiologicalCO,
  title={Biological characterisation of a recombinant Atlantic salmon type I interferon synthesized in Escherichia coli.},
  author={Ei Lin Ooi and Noel Verjan and Ikuo Hirono and Tomonori Nochi and Hidehiro Kondo and Takashi Aoki and Hiroshi Kiyono and Yoshikazu Yuki},
  journal={Fish & shellfish immunology},
  year={2008},
  volume={24 5},
  pages={506-13}
}
Type I (alpha/beta) interferons (IFNs) are a family of cytokines that stimulate the expression of numerous proteins that mediate an antiviral state in uninfected cells. Two Atlantic salmon (Salmo salar) IFN-alpha (SasaIFN-alpha1 & 2) genes have previously been cloned and both were found to contain a putative N-linked glycosylation site. Recombinant SasaIFN-alpha1 (rSasaIFN-alpha1) produced in eukaryotic systems has repeatedly been shown to confer antiviral properties. However, different IFN… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…