Biological-based optimization and volumetric modulated arc therapy delivery for stereotactic body radiation therapy.

@article{Diot2012BiologicalbasedOA,
  title={Biological-based optimization and volumetric modulated arc therapy delivery for stereotactic body radiation therapy.},
  author={Quentin Diot and Brian Kavanagh and Robert D. Timmerman and Moyed Miften},
  journal={Medical physics},
  year={2012},
  volume={39 1},
  pages={237-45}
}
PURPOSE To describe biological-based optimization and Monte Carlo (MC) dose calculation-based treatment planning for volumetric modulated arc therapy (VMAT) delivery of stereotactic body radiation therapy (SBRT) in lung, liver, and prostate patients. METHODS Optimization strategies and VMAT planning parameters using a biological-based optimization MC planning system were analyzed for 24 SBRT patients. Patients received a median dose of 45 Gy [range, 34-54 Gy] for lung tumors in 1-5 fxs and a… CONTINUE READING