Biological aspects of early osteoarthritis

  title={Biological aspects of early osteoarthritis},
  author={Henning Madry and Frank P. Luyten and Andrea Facchini},
  journal={Knee Surgery, Sports Traumatology, Arthroscopy},
Early OA primarily affects articular cartilage and involves the entire joint, including the subchondral bone, synovial membrane, menisci and periarticular structures. The aim of this review is to highlight the molecular basis and histopathological features of early OA. Selective review of literature. Risk factors for developing early OA include, but are not limited to, a genetic predisposition, mechanical factors such as axial malalignment, and aging. In early OA, the articular cartilage… CONTINUE READING


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