Biological and methodological implications of prostaglandin involvement in mouse brain lipid peroxidation measurements

Abstract

Enhanced cyclooxygenase-mediated prostaglandin (PG) turnover occurring during sacrifice and biochemical processing of tissues also generates malondialdehyde (MDA), a product of lipid peroxidation (LPO). Studies reporting on LPO estimated by thiobarbituric acid reactive substances (TBARS) have failed to consider such artefactual increases. This study reports… (More)
DOI: 10.1007/BF00971313

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