Biological and biomedical implications of the co-evolution of pathogens and their hosts
@article{Woolhouse2002BiologicalAB, title={Biological and biomedical implications of the co-evolution of pathogens and their hosts}, author={M. Woolhouse and J. Webster and E. Domingo and B. Charlesworth and B. Levin}, journal={Nature Genetics}, year={2002}, volume={32}, pages={569-577} }
Co-evolution between host and pathogen is, in principle, a powerful determinant of the biology and genetics of infection and disease. Yet co-evolution has proven difficult to demonstrate rigorously in practice, and co-evolutionary thinking is only just beginning to inform medical or veterinary research in any meaningful way, even though it can have a major influence on how genetic variation in biomedically important traits is interpreted. Improving our understanding of the biomedical… CONTINUE READING
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