Biological and biomechanical effects of vancomycin and meropenem in acrylic bone cement.


Antibiotic-loaded bone cement is extensively used in joint arthroplasty, but increasing bacteria resistance against common antibiotics has lead to a demand for alternative drugs. However, bone cement containing new additives must be characterized both biologically and mechanically. This study evaluated elution kinetics, antibacterial activity, and… (More)
DOI: 10.1016/j.arth.2007.10.010