Biological ages of adult men and women with Down's syndrome and its changes with aging.

@article{Nakamura1998BiologicalAO,
  title={Biological ages of adult men and women with Down's syndrome and its changes with aging.},
  author={Eitaro Nakamura and Shota Tanaka},
  journal={Mechanisms of ageing and development},
  year={1998},
  volume={105 1-2},
  pages={89-103}
}
In order to examine to what extent a gene dysregulation such as Down's syndrome (DS) causes the advance of global biological aging as well as segmental progeroid syndrome, 8 years of longitudinal data were gathered on 14 hematology and blood chemistry characteristics of five adult men and six adult women with DS and four adult men with cerebral palsy (CP). Biological age (BA) was established through the application of principal component analysis based on the data for the same 14 variables of… CONTINUE READING

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