Biological activity of the novel cyclic angiotensin II analogue [Sar1,Lys3,Glu5]ANG II

Abstract

This study was undertaken to investigate the biological activity of the cyclic amide-linked analogue of angiotensin II (ANG II), [Sar1,Lys3,Glu5]ANG II, in both ex vivo and in vivo experiments. This constrained analogue was designed on the basis of a recently suggested conformational model for ANG II-induced receptor activation, which is characterized by a… (More)
DOI: 10.1007/BF00128106

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