Biological activity of IgE specific for cross-reactive carbohydrate determinants.

Abstract

BACKGROUND The clinical relevance of IgE specific for cross-reactive carbohydrate determinants (CCDs) has been a matter of controversy. Until now, no convincing experiments have been performed to test the biologic significance of individual multivalent allergens that carry multiple carbohydrate epitopes. OBJECTIVE We sought to contribute to the… (More)

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