Biological activities of prymnesin-2 isolated from a red tide alga Prymnesium parvum.

@article{Igarashi1998BiologicalAO,
  title={Biological activities of prymnesin-2 isolated from a red tide alga Prymnesium parvum.},
  author={Tomoji Igarashi and Sayoko Aritake and Takeshi Yasumoto},
  journal={Natural toxins},
  year={1998},
  volume={6 1},
  pages={35-41}
}
Previously we isolated prymnesin-1 (PRM1) and prymnesin-2 (PRM2) as the major hemolytic and ichthyotoxic agents in the red tide organism Prymnesium parvum and disclosed the structure of PRM2 as a novel glycoside with unusual multiple functionality. PRM2 caused 50% hemolysis of a 1% suspension of dog red blood cells at 0.5 nM. The potency exceeded that of plant saponin by 50000 times. The lethality of PRM2 on freshwater fish Tanichthys albonubes was comparable to that of brevetoxin and also the… CONTINUE READING