• DOI:10.1016/0024-3205(86)90565-5
Corpus ID: 19881394

Biological activities of angiotensin II-(1-6)-hexapeptide and angiotensin II-(1-7)-heptapeptide in man.

@article{Kno1986BiologicalAO,
  title={Biological activities of angiotensin II-(1-6)-hexapeptide and angiotensin II-(1-7)-heptapeptide in man.},
  author={T. K{\^o}no and A. Taniguchi and H. Imura and F. Oseko and M. Khosla},
  journal={Life sciences},
  year={1986},
  volume={38 16},
  pages={
          1515-9
        }
}

T. Kôno, A. Taniguchi, +2 authors M. Khosla

Published 1986

Chemistry, Medicine

Life sciences

Biological activities of angiotensin II-(1-6)-hexapeptide [ANG-(1-6)] and angiotensin II-(1-7)-heptapeptide [ANG-(1-7)] were studied in 5 normal men and 3 patients with Bartter's syndrome. The angiotensins were infused iv in each subject from 0900 h to 0915 h at a rate of 21 nmol(16.8 micrograms)/kg X min and 18 nmol(16.2 micrograms)/kg X min for ANG-(1-6) and ANG-(1-7), respectively. In the normal men a significant rise in blood pressure was observed by the infusions of both peptides. Average… CONTINUE READING

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