Biological Significance of Urolithins, the Gut Microbial Ellagic Acid-Derived Metabolites: The Evidence So Far

@inproceedings{Espn2013BiologicalSO,
  title={Biological Significance of Urolithins, the Gut Microbial Ellagic Acid-Derived Metabolites: The Evidence So Far},
  author={Juan Carlos Esp{\'i}n and Mar Larrosa and Mar{\'i}a-Teresa Garc{\'i}a-Conesa and Francisco Tom{\'a}s Barber{\'a}n},
  booktitle={Evidence-based complementary and alternative medicine : eCAM},
  year={2013}
}
The health benefits attributed to pomegranate have been associated with its high content in polyphenols, particularly ellagitannins. This is also the case for other ellagitannin-containing fruits and nuts including strawberry, raspberry, blackberry, walnuts, and muscadine grapes. The bioavailability of ellagitannins and ellagic acid is however very low. These molecules suffer extensive metabolism by the gut microbiota to produce urolithins that are much better absorbed. Urolithins circulate in… CONTINUE READING