Biological Production of an Integrin αvβ3 Targeting Imaging Probe and Functional Verification

Abstract

The aim of the present study is to establish a bacterial clone capable of secreting an integrin αvβ3 targeting probe with bioluminescent and fluorescent activities, and to verify its specific targeting and optical activities using molecular imaging. A bacterial vector expressing a fusion of secretory Gaussia luciferase (sGluc), mCherry, and RGD (sGluc… (More)
DOI: 10.1155/2015/681012

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