Biological Processes Modulating Longevity across Primates: A Phylogenetic Genome-Phenome Analysis

@inproceedings{Muntan2018BiologicalPM,
  title={Biological Processes Modulating Longevity across Primates: A Phylogenetic Genome-Phenome Analysis},
  author={Gerard Muntan{\'e} and Xavier Farr{\'e} and Juan Antonio Mainez Rodr{\'i}guez and Cinta Pegueroles and David Anthony Hughes and Jo{\~a}o Pedro de Magalh{\~a}es and Toni Gabald{\'o}n and Arcadi Navarro},
  booktitle={Molecular biology and evolution},
  year={2018}
}
Aging is a complex process affecting different species and individuals in different ways. Comparing genetic variation across species with their aging phenotypes will help understanding the molecular basis of aging and longevity. Although most studies on aging have so far focused on short-lived model organisms, recent comparisons of genomic, transcriptomic, and metabolomic data across lineages with different lifespans are unveiling molecular signatures associated with longevity. Here, we examine… CONTINUE READING

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