Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy

Abstract

Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is the leading cause of transplant loss. Extensive research has been done to understand the pathogenesis… (More)
DOI: 10.1155/2014/482438

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