Biological Functionalities of Transglutaminase 2 and the Possibility of Its Compensation by Other Members of the Transglutaminase Family

@inproceedings{Odii2014BiologicalFO,
  title={Biological Functionalities of Transglutaminase 2 and the Possibility of Its Compensation by Other Members of the Transglutaminase Family},
  author={Benedict Onyekachi Odii and Peter J Coussons},
  booktitle={TheScientificWorldJournal},
  year={2014}
}
Transglutaminase 2 (TG2) is the most widely distributed and most abundantly expressed member of the transglutaminase family of enzymes, a group of intracellular and extracellular proteins that catalyze the Ca²⁺-dependent posttranslational modification of proteins. It is a unique member of the transglutaminase family owing to its specialized biochemical, structural and functional elements, ubiquitous tissue distribution and subcellular localization, and substrate specificity. The broad substrate… CONTINUE READING

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References

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Showing 1-10 of 136 references

The role of tissue transglutaminase in cell-matrix interactions

  • E. A. Zemskov, A. Janiak, J.Hang, A.Waghray, andA.M. Belkin
  • Frontiers in Bioscience, vol. 11, no. 1, pp. 1057…
  • 2006
Highly Influential
4 Excerpts

Mammalian transglutaminases: a family portrait

  • K.Mehta
  • Transglutaminases: Family of Enzymes with Diverse…
  • 2005
Highly Influential
4 Excerpts