Biological Activity of Staphylococcin 462: Bacteriocin from Staphylococcus aureus

@article{Hale1975BiologicalAO,
  title={Biological Activity of Staphylococcin 462: Bacteriocin from Staphylococcus aureus},
  author={E. M. Hale and R. D. Hinsdili},
  journal={Antimicrobial Agents and Chemotherapy},
  year={1975},
  volume={7},
  pages={74 - 81}
}
Staphylococcin 462 is a proteinaceous inhibitor produced by Staphylococcus aureus strain 462. In broth cultures, susceptible S. aureus strain 140 and 19 respond to treatment with the bacteriocin by stopping growth and cell division. Examination of macromolecular synthesis by measuring the incorporation of radioactive precursors revealed that S. aureus 140 stops synthesizing protein immediately. After exposure to staphylococcin 462, the synthesis of deoxyribonucleic acid and ribonucleic acid is… 
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