Biologic treatment or immunomodulation is not associated with postoperative anastomotic complications in abdominal surgery for Crohn's disease.

@article{ElHussuna2012BiologicTO,
  title={Biologic treatment or immunomodulation is not associated with postoperative anastomotic complications in abdominal surgery for Crohn's disease.},
  author={Alaa El-Hussuna and Jens Andersen and Thue Bisgaard and Per Jess and Mads Gram Henriksen and Jacob Oehlenschlager and Ole Thorlacius-Ussing and Gunnar P. Olaison},
  journal={Scandinavian journal of gastroenterology},
  year={2012},
  volume={47 6},
  pages={
          662-8
        }
}
OBJECTIVES There are concerns that biologic treatments or immunomodulation may negatively influence anastomotic healing. This study investigates the relationship between these treatments and anastomotic complications after surgery for Crohn's disease. PATIENTS AND METHODS Retrospective study on 417 operations for Crohn's disease performed at four Danish hospitals in 2000-2007. Thirty-two patients were preoperatively treated with biologics and 166 were on immunomodulation. In total, 154 were… CONTINUE READING
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