Biologic significance of receptor-binding cancer antigen expressed on SiSo cells (RCAS1) as a pivotal regulator of tumor growth through angiogenesis in human uterine cancer.

@article{Sonoda2007BiologicSO,
  title={Biologic significance of receptor-binding cancer antigen expressed on SiSo cells (RCAS1) as a pivotal regulator of tumor growth through angiogenesis in human uterine cancer.},
  author={Kenzo Sonoda and Shingo Miyamoto and Ayano Yamazaki and Hiroaki Kobayashi and Manabu Nakashima and Eisuke Mekada and Norio Wake},
  journal={Cancer},
  year={2007},
  volume={110 9},
  pages={1979-90}
}
BACKGROUND The expression of receptor-binding cancer antigen expressed on SiSo cells (RCAS1) is related significantly to the overall survival of patients with various cancers. RCAS1 reportedly induces apoptotic cell death in peripheral lymphocytes, which may contribute to the escape of tumor cells from immune surveillance. RCAS1 expression also has been related to tumor invasiveness and size in uterine cervical cancer. To clarify whether RCAS1 exacerbates tumor progression, the authors… CONTINUE READING
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