Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma.

@article{Tanaka1999BiologicSO,
  title={Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma.},
  author={Sakae Tanaka and Masaki Mori and Yasushi Sakamoto and Masatoshi Makuuchi and Keishi Sugimachi and Jack R Wands},
  journal={The Journal of clinical investigation},
  year={1999},
  volume={103 3},
  pages={341-5}
}
Human hepatocellular carcinoma (HCC) is generally a highly vascular tumor, but the mechanisms of neovascularization that permit rapid growth have not been defined. Angiopoietins (Ang) recently have been identified as ligands for vascular endothelial-specific Tie2 receptor tyrosine kinase and may be important growth factors in the generation of new blood vessels. We investigated Ang expression in 23 samples of HCC and paired adjacent uninvolved liver samples to determine if these genes have a… CONTINUE READING

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Hepatic incogenesis, IVD. Tumors of the liver

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