Biologic effects induced in vitro by PM10 from three different zones of Mexico City.

  title={Biologic effects induced in vitro by PM10 from three different zones of Mexico City.},
  author={Ernesto Alfaro-Moreno and Leticia Mart{\'i}nez and Claudia Ma Garc{\'i}a-Cuellar and James C. Bonner and Jeffrey C. Murray and Irma Rosas and Sergio Ponce de Le{\'o}n Rosales and Alvaro R Osornio-Vargas},
  journal={Environmental Health Perspectives},
  pages={715 - 720}
Exposure to urban airborne particles is associated with an increase in morbidity and mortality. There is little experimental evidence of the mechanisms involved and the role of particle composition. We assessed cytotoxicity (crystal violet assay), apoptosis [terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) or annexin V assay], DNA breakage (comet assay), and production of proinflammatory mediators [tumor necrosis factor Alpha (TNF-Alpha), interleukin 6 (IL-6… CONTINUE READING


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