Biologic and molecular characterization of producer and nonproducer clones from HUT-78 cells infected with a patient HIV isolate.

@article{Federico1989BiologicAM,
  title={Biologic and molecular characterization of producer and nonproducer clones from HUT-78 cells infected with a patient HIV isolate.},
  author={Maurizio P. M. Federico and Fausto Titti and Stefano Butt{\'o} and A Orecchia and Francesca Carlini and Brunella Taddeo and Beatrice Macchi and Nicola Maggiano and Paola Verani and Giovanni Battista Rossi},
  journal={AIDS research and human retroviruses},
  year={1989},
  volume={5 4},
  pages={385-96}
}
HUT-78 cells were infected with a reverse transcriptase (RT)-positive supernatant of a culture of peripheral blood lymphocytes (PBL) from an AIDS patient and then cloned. Of these clones, two have been isolated and characterized. Clone D10 is persistently and productively infected with an HIV variant. The clone F12, in spite of the presence of an integrated full-length HIV provirus, does not release virus particles in the medium. D10 and F12 clones substantially differ in terms of protein… CONTINUE READING

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The clone F12 , in spite of the presence of an integrated full - length HIV provirus , does not release virus particles in the medium . D10 and
The clone F12 , in spite of the presence of an integrated full - length HIV provirus , does not release virus particles in the medium . D10 and
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