Biokinetic model of radium in humans and beagles.

  title={Biokinetic model of radium in humans and beagles.},
  author={Erich Polig and Ray D Lloyd and Fred W. Bruenger and Scott C. Miller},
  journal={Health physics},
  volume={86 1},
A compartmental model of the distribution of radium in humans and young adult beagle dogs (approximately 500-550 d) is presented. The model consists of one soft tissue compartment and seven skeletal compartments for humans, and five skeletal compartments for beagles. The number of transfer parameters to be estimated was reduced by using remodeling rates of bone and imposing several constraints deduced from known features of bone physiology, radium metabolism, and autoradiographic analyses. The… CONTINUE READING