Bioinspired anchoring AgNPs onto micro-nanoporous TiO2 orthopedic coatings: Trap-killing of bacteria, surface-regulated osteoblast functions and host responses.

@article{Jia2016BioinspiredAA,
  title={Bioinspired anchoring AgNPs onto micro-nanoporous TiO2 orthopedic coatings: Trap-killing of bacteria, surface-regulated osteoblast functions and host responses.},
  author={Zhaojun Jia and Peng Xiu and Ming Li and Xuchen Xu and Yuying Shi and Yan Cheng and Shicheng Wei and Yufeng Zheng and Ting-fei Xi and Hong Cai and Zhong Jun Liu},
  journal={Biomaterials},
  year={2016},
  volume={75},
  pages={203-222}
}
The therapeutic applications of silver nanoparticles (AgNPs) against biomedical device-associated infections (BAI), by local delivery, are encountered with risks of detachment, instability and nanotoxicity in physiological milieus. To firmly anchor AgNPs onto modified biomaterial surfaces through tight physicochemical interactions would potentially relieve these concerns. Herein, we present a strategy for hierarchical TiO2/Ag coating, in an attempt to endow medical titanium (Ti) with… CONTINUE READING
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