Bioinspired Fibers Follow the Track of Natural Spider Silk

  title={Bioinspired Fibers Follow the Track of Natural Spider Silk},
  author={Manuel Elices and Gustavo V Guinea and Gustavo R. Plaza and Costas N. Karatzas and Christian Riekel and Fernando Agull{\'o}-Rueda and Rafael Daza and Jos{\'e} P{\'e}rez-Rigueiro},
The mechanical behavior and microstructure of bioinspired fibers spun from solutions of recombinant spidroin-like proteins were extensively characterized, and compared with those of natural spider silk fibers. It is confirmed that high performance bioinspired fibers indistinguishable from natural spider silk up to large strains can be produced through genetic engineering and conventional spinning technologies. It is also found that fibers spun from spidroin-like proteins that contain different… 
Characterization of natural and biomimetic spider silk fibers
Spider silk produced by orb-weaving spiders reveals fascinating mechanical properties, in particular, its unique combination of high tensile strength and elasticity, distinguishing it from most other
Correlation between processing conditions, microstructure and mechanical behavior in regenerated silkworm silk fibers
Regenerated silkworm fibers spun through a wet-spinning process followed by an immersion postspinning drawing step show a work to fracture comparable with that of natural silkworm silk fibers in a
Bioinspired and biomimetic silk spinning
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An overview on recent developments concerning genetic engineering and chemical modification of recombinant silk proteins will be given, outlining the potential provided by recombinant spider silk-chimeric proteins and spider Silk-inspired polymers (combining synthetic polymers and spider silk peptides).
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The different approaches of biotechnological production and the advances in material processing toward various applications will be reviewed.
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The results show that the electrospun RSSP fibrous scaffold had good biocompatibility with PC 12 cells and was affected by the solvent used in the coagulation bath.
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Spider silk is one of the best illustrations of biomimetism. Thanks to a complex hierarchical structure, this fibre exhibits remarkable characteristics, especially renowned tensile properties. Silk
Mechanical performance of spider silk is robust to nutrient-mediated changes in protein composition.
It is found that spidroin expression differed across treatments but that its influence on mechanics was minimal, and increased alignment in the amorphous region and to a lesser extent in the crystalline region led to increased fiber strength and extensibility in spiders on protein rich diets.
Spider silk as a blueprint for greener materials: a review
Spider silk exhibits remarkable properties, especially its well-known tensile performances. They rely on a complex nanostructured hierarchical organisation that studies progressively elucidate.
Recombinant production of spider silk proteins.


Supramolecular organization of regenerated silkworm silk fibers.
Old Silks Endowed with New Properties
High-performance regenerated silkworm Bombyx mori silk fibers with new properties that mimic those of spider silk can be produced through a wet spinning process modified with an immersion
Recovery in spider silk fibers
The extreme toughness of spider silk is dependent on the silk's ability to dissipate most of the mechanical energy imparted to the fiber during loading processes through irreversible deformations.
Similarities and Differences in the Supramolecular Organization of Silkworm and Spider Silk
The characterization of silkworm and spider silk from nanometer to micrometer scale by atomic force microscopy reveals similar design principles despite the distance of their spinning organisms in
Proline and processing of spider silks.
These relationships, in combination with protein sequence data, support the hypothesis that the proline-related motif, that is, GPGXX, may play a key role in silk and explain the interspecific variability of spider dragline silk.
Spider Silk Fibers Spun from Soluble Recombinant Silk Produced in Mammalian Cells
The wet spinning of silk monofilaments spun from a concentrated aqueous solution of soluble rc–spider silk protein (ADF-3; 60 kilodaltons) under modest shear and coagulation conditions showed toughness and modulus values comparable to those of native dragline silks but with lower tenacity.
Effect of water on Bombyx mori regenerated silk fibers and its application in modifying their mechanical properties
The effect of water on regenerated silkworm silk fibers has been studied and compared with that of water on natural silkworm silk fibers. Regenerated fibers are spun from an
Mechanical behavior of silk during the evolution of orb-web spinning spiders.
The comparison of silks spun by spiders belonging to different phylogenetic groups has revealed that evolution locked in many of the important properties of spider silks very early in the history of orb-web weaving spiders, despite the fact that the silk gland system is relatively isolated in physiological terms from the rest of the organism and should thus mutate quickly.
Molecular and nanostructural mechanisms of deformation, strength and toughness of spider silk fibrils.
This model develops the first spider silk mesoscale model, bridging the scales from Angstroms to tens to potentially hundreds of nanometers, and demonstrates that the specific nanoscale combination of a crystalline phase and a semiamorphous matrix is crucial to achieve the unique properties of silks.
Spider silk as rubber
The silks produced by spiders are exceptional structural materials. Although their tensile strengths are similar to those of cellulose, collagen and chitin, their extensibilities are considerably