Bioinformatics for Next Generation Sequencing Data

  title={Bioinformatics for Next Generation Sequencing Data},
  author={Alberto Magi and Matteo Benelli and Alessia Gozzini and Francesca Girolami and Francesca Torricelli and Maria Luisa Brandi},
The emergence of next-generation sequencing (NGS) platforms imposes increasing demands on statistical methods and bioinformatic tools for the analysis and the management of the huge amounts of data generated by these technologies. Even at the early stages of their commercial availability, a large number of softwares already exist for analyzing NGS data. These tools can be fit into many general categories including alignment of sequence reads to a reference, base-calling and/or polymorphism… CONTINUE READING