Corpus ID: 14266037

Bioinformatics-based strategies for rapid microorganism identification by mass spectrometry

@article{Demirev2004BioinformaticsbasedSF,
  title={Bioinformatics-based strategies for rapid microorganism identification by mass spectrometry},
  author={Plamen A. Demirev and Andrew B. Feldman and Jeffrey S. Lin},
  journal={Johns Hopkins Apl Technical Digest},
  year={2004},
  volume={25},
  pages={27-37}
}
We review approaches for microorganism identification that exploit the wealth of information in constantly expanding proteome databases. Masses of an organism's protein biomarkers are experimentally determined and matchedagainst sequence-derived masses of proteins, -found together with their source organisms in proteome databases. The source organisms are ranked according to the matches, resulting in microorganism identification. Statistical analysis of proteome uniqueness across organisms in a… Expand

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