Corpus ID: 23065155

Bioinformatics-based design of novel antigenic B-cell linear epitopes of Deinagkistrodon acutus venom.

@article{Cao2016BioinformaticsbasedDO,
  title={Bioinformatics-based design of novel antigenic B-cell linear epitopes of Deinagkistrodon acutus venom.},
  author={Y. Cao and G-N Guo and G. Zhu and Z. Tian and Y-J Gou and C. Chen and M-H Liu},
  journal={European review for medical and pharmacological sciences},
  year={2016},
  volume={20 4},
  pages={
          781-7
        }
}
  • Y. Cao, G-N Guo, +4 authors M-H Liu
  • Published 2016
  • Biology, Medicine
  • European review for medical and pharmacological sciences
  • OBJECTIVE With the help of bioinformatics analysis, we wished to develop a novel antivenom against the Deinagkistrodon (D.) acutus snake venom using B-cell linear epitopes of three primary toxins (serine protease, metalloprotease, and phospholipase A2). MATERIALS AND METHODS cDNA sequences of three toxins of D. acutus venom were retrieved from the NCBI database. B-cell linear epitopes were predicted using DNAStar and the website server software provided by IEDB. Then, the sequences of the… CONTINUE READING
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