Bioinformatics and Moonlighting Proteins

  title={Bioinformatics and Moonlighting Proteins},
  author={Sergio Barroso Hern{\'a}ndez and Luis Franco and Alejandra Calvo and Gabriela Ferragut and Antoni Hermoso and Isaac Amela and Antonio Bermejo G{\'o}mez and Enrique Querol and Juan Cedano},
  booktitle={Front. Bioeng. Biotechnol.},
Multitasking or moonlighting is the capability of some proteins to execute two or more biochemical functions. Usually, moonlighting proteins are experimentally revealed by serendipity. For this reason, it would be helpful that Bioinformatics could predict this multifunctionality, especially because of the large amounts of sequences from genome projects. In the present work, we analyze and describe several approaches that use sequences, structures, interactomics, and current bioinformatics… CONTINUE READING
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