Bioinformatics analysis of molecular mechanisms involved in intervertebral disc degeneration induced by TNF-α and IL-1β.

@article{Xu2016BioinformaticsAO,
  title={Bioinformatics analysis of molecular mechanisms involved in intervertebral disc degeneration induced by TNF-$\alpha$ and IL-1$\beta$.},
  author={Feng Xu and F. Gao and Yadong Liu and Zhenyu Wang and Xinming Zhuang and Zhigang Qu and Hui-Jie Ma and Yi Liu and Chang-feng Fu and Qi Zhang and Xiaoying Duan},
  journal={Molecular medicine reports},
  year={2016},
  volume={13 3},
  pages={
          2925-31
        }
}
The present study aimed to explore the molecular mechanisms associated with intervertebral disc degeneration (IDD) induced by tumor necrosis factor (TNF)‑α and interleukin (IL)‑1β. The microarray dataset no. GSE42611 was downloaded from the Gene Expression Omnibus database. The differentially expressed genes (DEGs) between four experimental nucleus pulposus samples and four control nucleus pulposus samples were analyzed. Subsequently, Gene Ontology (GO) and pathway enrichment analyses of DEGs… 
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