Bioinformatics Methods for the Analysis of Hepatitis Viruses

  title={Bioinformatics Methods for the Analysis of Hepatitis Viruses},
  author={Francesco Moriconi and Michael R. Beard and Lilly K W Yuen},
  journal={Antiviral Therapy},
  pages={531 - 539}
HBV and HCV are the only hepatotropic viruses capable of establishing chronic infections. More than 500 million people worldwide are estimated to have chronic infections with HBV and/or HCV, and they have an increased risk of developing liver complications, such as cirrhosis or hepatocellular carcinoma. During the past decade, several antiviral agents including immune-modulatory drugs and nucleoside/nucleotide analogues have been approved for the treatment of HBV and HCV infections. In recent… 

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