Bioinformatic insight into the unity and diversity of cytochromes P450.

@article{Lisitsa2003BioinformaticII,
  title={Bioinformatic insight into the unity and diversity of cytochromes P450.},
  author={Andrey Valerievich Lisitsa and Alexander Archakov and Paul Lewi and Paul Jan\ssen},
  journal={Methods and findings in experimental and clinical pharmacology},
  year={2003},
  volume={25 9},
  pages={733-45}
}
For the past few decades, cytochromes P450 (CYPs) have been the subject of extensive research, owing to the ability of these enzymes to serve as drug targets as well as to their active participation in drug metabolism. Other varieties and functions of CYPs have been discovered and this superfamily currently comprises over 2000 different protein species. In… CONTINUE READING