Bioinformatic identification of proteins with tissue-specific expression for biomarker discovery

@inproceedings{Prassas2012BioinformaticIO,
  title={Bioinformatic identification of proteins with tissue-specific expression for biomarker discovery},
  author={Ioannis Prassas and Caitlin C Chrystoja and Shalini Makawita and Eleftherios P Diamandis},
  booktitle={BMC medicine},
  year={2012}
}
BACKGROUND There is an important need for the identification of novel serological biomarkers for the early detection of cancer. Current biomarkers suffer from a lack of tissue specificity, rendering them vulnerable to non-disease-specific increases. The present study details a strategy to rapidly identify tissue-specific proteins using bioinformatics. METHODS Previous studies have focused on either gene or protein expression databases for the identification of candidates. We developed a… CONTINUE READING
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