Bioinformatic Approach to Identify Penultimate Amino Acids Efficient for N-Terminal Methionine Excision


More than half of proteins in prokaryotes and eukaryotes undergo N-terminal methionine excision (NME). While it is known that the penultimate amino acid affects the efficiency of NME in several bacterial and eukaryotic species, it is experimentally difficult and tedious to verify which amino acid at the penultimate site (the site after initiator Met) is the… (More)


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