Bioinformatic Analysis of Antigenic Proteins in Celiac Disease.

Abstract

Investigation of the chemistry of the gliadin proteins has played an important role in our comprehension of how celiac disease (CoD) develops and progresses as a response to challenge with this immune stimulus. Studies in this area have implicated gut enzymes, tissue transglutaminase-mediated deamidation, and peptide binding affinity for the HLA-DQ2 and DQ8… (More)
DOI: 10.1007/978-1-4939-2839-2_16

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