Biogenic gold nano-triangles: cargos for anticancer drug delivery.

@article{Dharmatti2014BiogenicGN,
  title={Biogenic gold nano-triangles: cargos for anticancer drug delivery.},
  author={Roopa Dharmatti and Chinmay Phadke and Ashmi Mewada and Mukeshchand Thakur and Sunil Pandey and Madhuri Sharon},
  journal={Materials science & engineering. C, Materials for biological applications},
  year={2014},
  volume={44},
  pages={
          92-8
        }
}
We present synthesis of biogenic gold nano triangles (GNTs) using Azadirachta indica leaf extract at inherent pH (5.89) and its application in efficient drug delivery of doxorubicin (DOX) (anticancer drug). The main idea was to take advantage of large surface area of GNTs which has 3 dimensions and use the plant peptides coated on these triangles as natural linkers for the attachment of DOX. Sucrose density gradient centrifugation (SDGC) and dialysis methods were used for separation of the GNT… CONTINUE READING

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