Biogenic amine activity in response to fluoxetine and desipramine in differentially reared rhesus monkeys.

@article{Clarke1999BiogenicAA,
  title={Biogenic amine activity in response to fluoxetine and desipramine in differentially reared rhesus monkeys.},
  author={A S Clarke and M. Ebert and Dennis E. Schmidt and William T. McKinney and Gary W. Kraemer},
  journal={Biological psychiatry},
  year={1999},
  volume={46 2},
  pages={221-8}
}
BACKGROUND It has been hypothesized that adverse early experience may be a mechanism by which children become vulnerable to later psychopathology via alteration of neurochemical or hormonal systems associated with such disorders. Such effects may in turn affect later responses to pharmacologic agents that act on these systems. METHODS In this study, 18 mother-reared (MR) and 18 peer-reared (PR) rhesus monkeys experienced six 1-week separations from cagemates interspersed with 1-week reunions… CONTINUE READING

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