Biogenesis of the protein import channel Tom40 of the mitochondrial outer membrane: intermembrane space components are involved in an early stage of the assembly pathway.

Abstract

Tom40 forms the central channel of the preprotein translocase of the mitochondrial outer membrane (TOM complex). The precursor of Tom40 is encoded in the nucleus, synthesized in the cytosol, and imported into mitochondria via a multi-step assembly pathway that involves the mature TOM complex and the sorting and assembly machinery of the outer membrane (SAM… (More)

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@article{Wiedemann2004BiogenesisOT, title={Biogenesis of the protein import channel Tom40 of the mitochondrial outer membrane: intermembrane space components are involved in an early stage of the assembly pathway.}, author={Nils Wiedemann and Kaye N. Truscott and Sylvia Pfannschmidt and Bernard Guiard and Chris Meisinger and Nikolaus Pfanner}, journal={The Journal of biological chemistry}, year={2004}, volume={279 18}, pages={18188-94} }