Biogenesis of multilamellar bodies via autophagy.

  title={Biogenesis of multilamellar bodies via autophagy.},
  author={Mehrdad Hariri and G Millane and Martin Guimond and Ginette Guay and J. W. Dennis and Ivan Robert Nabi},
  journal={Molecular biology of the cell},
  volume={11 1},
Transfection of Mv1Lu mink lung type II alveolar cells with beta1-6-N-acetylglucosaminyl transferase V is associated with the expression of large lysosomal vacuoles, which are immunofluorescently labeled for the lysosomal glycoprotein lysosomal-associated membrane protein-2 and the beta1-6-branched N-glycan-specific lectin phaseolis vulgaris leucoagglutinin. By electron microscopy, the vacuoles present the morphology of multilamellar bodies (MLBs). Treatment of the cells with the lysosomal… CONTINUE READING