Biogenesis of antibiotics—viewing its history and glimpses of the future

@article{Spek2016BiogenesisOA,
  title={Biogenesis of antibiotics—viewing its history and glimpses of the future},
  author={Jaroslav Sp{\'i}{\vz}ek and Karel Sigler and Tom{\'a}{\vs} Řezanka and Arny Demain},
  journal={Folia Microbiologica},
  year={2016},
  volume={61},
  pages={347-358}
}
This review aims at comparing some historical data with the current situation in the study of biogenesis of natural compounds, antibiotics in the first place. Biogenesis of tetracyclines and cycloheximide and related compounds serves as example. Examples of molecular biological and bioinformatics methods used in the study of antibiotic biogenesis are… CONTINUE READING