Biogenesis and significance of central nervous system myelin.

  title={Biogenesis and significance of central nervous system myelin.},
  author={M Mateo Paz Sold{\'a}n and I. Pirko},
  journal={Seminars in neurology},
  volume={32 1},
The central nervous system is composed of neurons and glia cells. Although neurons have long been considered the functionally important cells, an ever-expanding body of research has revealed many critical functions of neuroglia. Among these, the myelin sheath elaborated by oligodendrocytes acts as a dynamic partner to the axons it enwraps and can no longer be considered as an inert membrane. In addition to its best known roles of providing insulation and optimizing conduction velocity… CONTINUE READING