Biogenesis and function of mouse mammary epithelium depends on the presence of functional α-catenin

Abstract

Alpha-catenin is a structural molecule and essential to the function of epithelial adherens junctions. Its role in the morphogenesis of mammary epithelium was explored using experimental mouse genetics. Since loss of alpha-catenin in mice leads to embryonic lethality, the alpha-catenin gene was flanked by loxP sites and inactivated in mammary epithelium… (More)
DOI: 10.1016/j.mod.2003.09.007

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Cite this paper

@article{Nemade2004BiogenesisAF, title={Biogenesis and function of mouse mammary epithelium depends on the presence of functional α-catenin}, author={Rashmi V Nemade and Brian Bierie and Masahiro Nozawa and C{\'e}line Bry and Gilbert H Smith and Valeri I Vasioukhin and Elaine Fuchs and Lothar Hennighausen}, journal={Mechanisms of Development}, year={2004}, volume={121}, pages={91-99} }