Biofortified black beans in a maize and bean diet provide more bioavailable iron to piglets than standard black beans.

@article{Tako2009BiofortifiedBB,
  title={Biofortified black beans in a maize and bean diet provide more bioavailable iron to piglets than standard black beans.},
  author={Elad Tako and Jos{\'e} Mois{\'e}s Laparra and Raymond Philip Glahn and Ross M. Welch and Xin Gen Lei and Stephen E. Beebe and Dennis Dean Miller},
  journal={The Journal of nutrition},
  year={2009},
  volume={139 2},
  pages={
          305-9
        }
}
Our objective was to compare the capacities of biofortified and standard black beans (Phaseolus vulgaris L.) to deliver iron (Fe) for hemoglobin (Hb) synthesis. Two lines of black beans, one standard and the other biofortified (high) in Fe (71 and 106 microg Fe/g, respectively), were used. Maize-based diets containing the beans were formulated to meet the nutrient requirements for swine except for Fe (Fe concentrations in the 2 diets were 42.9 +/- 1.2 and 54.6 +/- 0.9 mg/kg). At birth, pigs… 

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References

SHOWING 1-10 OF 29 REFERENCES
Genetic selection for enhanced bioavailable levels of iron in bean (Phaseolus vulgaris L.) seeds.
TLDR
The bioavailability of Fe from 24 select genotypes of bean (Phaseolus vulgaris L.) seeds containing a range of concentrations of Fe, myo-inositol pentaphosphate plus phytic acid, and tannin seed concentrations was studied using a rat model, finding no significant correlation between the Fe concentration in different bean genotypes and Fe bioavailability to rats attributable to variations in IP5+IP6 or tannins.
Supplemental dietary inulin affects the bioavailability of iron in corn and soybean meal to young pigs.
TLDR
It is concluded that supplementing 4% inulin improved utilization of intrinsic iron in the corn and soybean meal diet by young pigs, and this benefit was associated with soluble Fe and sulfide concentrations but not pH or phytase activity in the digesta.
Iron-biofortified rice improves the iron stores of nonanemic Filipino women.
TLDR
Consumption of biofortified rice, without any other changes in diet, is efficacious in improving iron stores of women with iron-poor diets in the developing world.
Effects of dietary iron supplementation on growth performance, hematological status, and whole-body mineral concentrations of nursery pigs.
TLDR
Results suggest that Fe contributed by feed ingredients was not sufficient to maintain indices of Fe status and the lessening of a pig's Fe stores during this rapid growth period may result in the occurrence of anemia during the subsequent grower and finisher periods.
Biofortification of staple food crops.
TLDR
Scientific evidence shows biofortification as being important in the armamentarium for controlling micronutrient deficiencies and the challenge is to get producers and consumers to accept biofortified crops and increase their intake of the target nutrients.
Food-based strategies to meet the challenges of micronutrient malnutrition in the developing world
TLDR
Linking community development policies to national programmes for the alleviation of hunger and malnutrition, with an emphasis on increasing the variety of foods consumed, is probably the best strategy for improving micronutrient malnutrition sustainably.
Impact of Feeding High-Iron Rice on Plasma Iron, Hemoglobin and Red Blood Cell Variables of Early-Weaned Piglets
TLDR
Modifications regarding study design, study duration and subject’s growth rate are recommended to increase the possibility of detecting changes in the iron status triggered by diets having small differences in dietary iron.
Nutrition and health implications of dry beans: a review.
The nutrient composition of dry beans makes them ideally suited to meet two major dietary recommendations for good health--increased intake of starches and complex carbohydrates and decreased
Effect of ascorbic acid intake on nonheme-iron absorption from a complete diet.
TLDR
The facilitating effect of vitamin C on iron absorption from a complete diet is far less pronounced than that from single meals, which may explain why several prior studies did not show a significant effect on iron status of prolonged supplementation with vitamin C.
...
...