Biofilm maturity studies indicate sharp debridement opens a time- dependent therapeutic window.

@article{Wolcott2010BiofilmMS,
  title={Biofilm maturity studies indicate sharp debridement opens a time- dependent therapeutic window.},
  author={R. Wolcott and K. Rumbaugh and G. James and G. Schultz and P. Phillips and Q. Yang and C. Watters and P. Stewart and S. Dowd},
  journal={Journal of wound care},
  year={2010},
  volume={19 8},
  pages={
          320-8
        }
}
OBJECTIVE To investigate the hypothesis that newly formed wound biofilms (or bioburdens) are more susceptible to antimicrobial treatment. METHOD Four separate and distinct models were performed by four separate biofilm research laboratories to evaluate the resistance of biofilms to antimicrobial treatments over time. These included a drip-flow biofilm model along with a hydrodebridement study, a porcine skin punch biopsy ex vivo model, a mouse chronic wound model and clinical longitudinal… Expand
Comparing the Effectiveness of Polymer Debriding Devices Using a Porcine Wound Biofilm Model
Development of a novel ex vivo porcine skin explant model for the assessment of mature bacterial biofilms
  • Q. Yang, P. Phillips, +4 authors G. Schultz
  • Biology, Medicine
  • Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
  • 2013
Clinically Addressing Biofilm in Chronic Wounds.
Efficacy of a surfactant‐based wound dressing on biofilm control
  • S. Percival, D. Mayer, A. Salisbury
  • Medicine
  • Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
  • 2017
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 43 REFERENCES
A Wound‐Isolated Pseudomonas aeruginosa Grows a Biofilm In Vitro Within 10 Hours and Is Visualized by Light Microscopy
Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms
Biofilms in chronic wounds
  • G. James, E. Swogger, +5 authors P. Stewart
  • Biology, Medicine
  • Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
  • 2008
Mechanisms of antibiotic resistance in bacterial biofilms.
  • P. Stewart
  • Biology, Medicine
  • International journal of medical microbiology : IJMM
  • 2002
Mechanisms of biofilm resistance to antimicrobial agents.
Survival strategies of infectious biofilms.
Phenotypic characterization of Streptococcus pneumoniae biofilm development.
...
1
2
3
4
5
...