Biofilm-derived Legionella pneumophila evades the innate immune response in macrophages

  title={Biofilm-derived Legionella pneumophila evades the innate immune response in macrophages},
  author={Arwa Abu Khweek and Natalia S. Fern{\'a}ndez D{\'a}vila and Kyle Caution and Anwari Akhter and Basant A. Abdulrahman and Mia F. Tazi and Hoda A. Hassan and Laura A. Novotny and Lauren O. Bakaletz and Amal O. Amer},
  booktitle={Front. Cell. Infect. Microbiol.},
Legionella pneumophila, the causative agent of Legionnaire's disease, replicates in human alveolar macrophages to establish infection. There is no human-to-human transmission and the main source of infection is L. pneumophila biofilms established in air conditioners, water fountains, and hospital equipments. The biofilm structure provides protection to the organism from disinfectants and antibacterial agents. L. pneumophila infection in humans is characterized by a subtle initial immune… CONTINUE READING
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